NIH released a notice, NOT-OD-15-039, which provides information about a new simplified policy for late application submission. Specifically, there is now a two week window of consideration after the application due date, during which time NIH might consider accepting a late application.
This is a significant change from previous policy, which tied different late windows of consideration to different types of applications, and provided no late window of consideration for applications submitted to any RFA (Request for Applications) or PAR (Program Announcement) with special application due dates.